Tag: #molecular-biology

Casgevy: What the First FDA-Approved CRISPR Therapy Actually Does

On December 8, 2023, the FDA approved Casgevy (exagamglogene autotemcel, or exa-cel), developed by Vertex Pharmaceuticals and CRISPR Therapeutics. It was the fi…

#crispr #cas9 #gene-editing #molecular-biology

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Germline Editing: He Jiankui, Lulu and Nana, and Where the Line Gets Drawn

In November 2018, He Jiankui announced at a conference in Hong Kong that he had used CRISPR to edit human embryos that were subsequently implanted and carried t…

#crispr #cas9 #gene-editing #molecular-biology

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Why Does DNA Have a Double Helix? The Chemistry Behind Life's Signature Structure

You've seen the image a thousand times — the twisting ladder of life. But here's the thing: nobody designed the double helix for elegance. The shape is a *che…

#biology #dna #chemistry #genetics

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How Does CRISPR Know Where to Cut? The Molecular Search Engine Inside Cas9

The thing that surprises most people about CRISPR isn't that it works — it's how surprisingly mechanical the process is. There's no magic. Cas9 is a protein wit…

#crispr #cas9 #gene-editing #biology

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