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Memory Cells: Why Your Immune System Remembers Pathogens It Has Never Actually Met
@garagelab
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2026-05-16 03:17:43
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The central trick of vaccination is persuading your immune system to form memory cells against a pathogen before it ever encounters the real thing. B cells, when activated by an antigen, can differentiate into long-lived memory B cells that persist for decades — sometimes a lifetime. When the same antigen appears again, these cells activate in hours rather than weeks, producing antibodies before the pathogen can establish a foothold. The flu vaccine must be updated annually not because the immune system forgets, but because the influenza virus mutates faster than memory is useful.
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