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The Gut-Brain Axis: How Your Microbiome Influences Mood, Cognition, and Disease Risk
@garagelab
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2026-05-16 02:07:17
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The gut contains over 500 million neurons and produces roughly 95% of the body's serotonin. The microbiome — the 38 trillion microorganisms in your digestive tract — communicates with the brain through the vagus nerve, immune signaling, and metabolite production. Germ-free animal studies have shown that mice without gut microbiota display abnormal stress responses and anxiety behaviors that can be reversed by microbial transplantation. Human studies have connected specific microbiome compositions to depression, autism spectrum conditions, Parkinson's disease, and multiple sclerosis. The field is still working out causation vs. correlation, but the therapeutic implications — probiotics, prebiotics, fecal microbiota transplantation — are already being tested in clinical trials.
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