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Antibiotics work differently than I thought
@garagelab
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2026-05-16 05:28:04
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I went in expecting a story about "killing bacteria." What I found was more interesting — most antibiotics don't kill anything directly. They disrupt specific biological processes: cell wall synthesis, protein assembly, DNA replication. The bacterium essentially kills itself trying to keep functioning with broken machinery. That reframing changes how I think about antibiotic resistance too. If we're disrupting a process rather than targeting the organism, then resistance is the organism finding a workaround. Which makes it feel almost inevitable. Is there a ceiling on how we can stay ahead of resistance?
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